Pepper_rat
Well-Known Member
I’d like to preface this by saying that I’m one semester away from a bachelor’s degree in biology so I have some knowledge in this area however I am not an expert.
I’ve recently learned about a supplement called nicotinamide mononucleotide (NMN). To put it simply, NMN is the precursor to NAD which is a form of energy that is used throughout the body. As the body (rat, human, or other vertebrate) ages, the amount of NMN and subsequently the amount of NMN throughout the body decreases. This decrease is what leads, indirectly and directly, to what we consider the “symptoms” of aging, for example weight gain, mental degradation, joint and muscle problems, and more. For several years, scientists have been testing out the use of NMN as a supplement to help to mitigate these effects of aging. They have found amazing results including almost a reversal in age related issues in elderly mice.
My first thought after seeing this was, could it work to help my rats live longer and healthier lives? I have been searching since I met my heart rat, Pepper, for ways to help her live as long and as comfortable a life as possible. This might be a way. Currently NMN has been used in dogs, mice, and is going through trials in humans but it is not considered a controlled substance and is available for purchase. They have found no negative side effects in any animals and it has only been able to improve their lives. I will add links to the studies I’ve read but I would love to hear other’s ideas and opinions regarding this. I haven’t found a study in rats, but I know that if they’ve done studies in mice and humans then it should be fine for rats. I will be buying some as a supplement and trying it with pepper and my other elderly girl as I believe if there’s any way I can keep my sweet girl heathy and happy for her second birthday, I will. Let me know what you think!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238909/https://www.nmn.com/topic?filters=basic-research,longevityhttps://www.frontiersin.org/articles/10.3389/fphar.2020.604404/fullhttps://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(16)30495-8https://www.mdpi.com/1422-0067/21/11/3756/htm
I’ve recently learned about a supplement called nicotinamide mononucleotide (NMN). To put it simply, NMN is the precursor to NAD which is a form of energy that is used throughout the body. As the body (rat, human, or other vertebrate) ages, the amount of NMN and subsequently the amount of NMN throughout the body decreases. This decrease is what leads, indirectly and directly, to what we consider the “symptoms” of aging, for example weight gain, mental degradation, joint and muscle problems, and more. For several years, scientists have been testing out the use of NMN as a supplement to help to mitigate these effects of aging. They have found amazing results including almost a reversal in age related issues in elderly mice.
My first thought after seeing this was, could it work to help my rats live longer and healthier lives? I have been searching since I met my heart rat, Pepper, for ways to help her live as long and as comfortable a life as possible. This might be a way. Currently NMN has been used in dogs, mice, and is going through trials in humans but it is not considered a controlled substance and is available for purchase. They have found no negative side effects in any animals and it has only been able to improve their lives. I will add links to the studies I’ve read but I would love to hear other’s ideas and opinions regarding this. I haven’t found a study in rats, but I know that if they’ve done studies in mice and humans then it should be fine for rats. I will be buying some as a supplement and trying it with pepper and my other elderly girl as I believe if there’s any way I can keep my sweet girl heathy and happy for her second birthday, I will. Let me know what you think!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238909/https://www.nmn.com/topic?filters=basic-research,longevityhttps://www.frontiersin.org/articles/10.3389/fphar.2020.604404/fullhttps://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(16)30495-8https://www.mdpi.com/1422-0067/21/11/3756/htm
